Microbiology of the Vagina

Lactobacilli are strongly associated with reduced risks of infections by reproductive tract pathogens, including HIV-1 , HSV-2  Trichomonas vaginalis , Neisseria gonorrhoeae and Chlamydia trachomatis , as well as the multiple species of bacteria associated with bacterial vaginosis (BV)  Lactobacilli are tolerated by vaginal epithelial cells and inhibit induction of pro‐inflammatory cytokines. Increased exposure to […]

The vaginal microbiota has great significance in maintaining vaginal health and protecting the host from disease. Vaginal lactobacilli produce lactic acid, that provide protection against reproductive tract infections. This acidification of the vagina to a pH of 3.0–4.5 results in inhibition of the growth of other bacteria.  Lactobacilli bind to the surface of vaginal epithelial